Biosensors technology: DNA microarray, peptide ans protein -soluble or not soluble- analysis chips, and cell analysis biochips. The course will permit to deepen some of the main physical or biophysical principles used for the fabrication and use of these biosensors:
Fabrication principle of DNA microarrays
Soluble protein or peptide biochips
- 2D electrophoresis
- Mass spectrometer coupling
- Peptide microarrays - surface functionnalization aspects
Membrane protein biochips
- Planar patch clamp technology
- Miniaturization and noise
Cell biochips
- Cell sorting using DEP, or microfluidic principles
- Cell detection and analysis using impedancemetry
- Ampérometric detection on a chip - advantage of miniaturized electrodes
Nanobiotechnologies; characterization, design and application and to clarified the potential of nanotechnology in diagnosis and therapy
Intracellular engineering at nanometer scale; e.g. cellular machineries
Nanoimaging in biology and medicine
Nanoparticles and diagnosis
Biosensors
Liposomes as pharmaceuticals carriers
Labchips and diagnosis
Nanomedecine and cancer