I Dosage form development: formulation and characterisations (homogenous systems, heterogeneous system, liquids, semisolids, solids forms)
Dosage form-therapeutical-biopharmaceutical correlations.
II LADME system in preclinical development and prediction in silico
III Evaluation of release, absorption, biopharmacy and distribution of drugs ; experimental approaches.
IV Drug metabolism and drug-drug interactions in research and development
Metabolism and drugs interactions , basic concepts on drug metabolism and drug interactions; Inhibition and induction studies, In vitro and in vivo predictions - Drug transporters , Basic concepts on drug transporters,Enzyme and transporter mediated drug-drug interactionsAcquiredSkills :
-Knowledge of formulation for therapeutical effect (choice of dosage with biopharmaceutical parameters)
-Knowledge of LADME studies and used in medicine development
-Knowledge of experimental studies and prediction methods of LADME